Scientists are Successfully Capturing Human Genetic Diversity
The research by scientists and technological advancements expand the capturing of the genetics of humanity.
The Pangenome Project, an initiative to better understand the diversity of people worldwide, published its first wave of results this week. The results should help scientists understand how genetics affects our health and evolution journey.
The 20th anniversary of the Human Genome Project officially ended this April. Thousands of scientists worked together to decode and translate most of the genetic information that makes up a person’s genetic code.
The project outcomes and discoveries ushered in a new era of scientific study and have helped develop advancements in cancer treatment, genetic engineering, biology, and more.
The project’s researchers were aware that their work needed to be completed even at the time, making only about 90% of the genome had been sequenced (the first actual complete genome sequence was achieved in 2022).
On May 10, the team published research in Nature Journal describing two genome studies and the first draught of their human pangenome reference.
There are 47 members of the pangenome team who represent various ethnic groups in Asia, Africa, and South America. And it contains 1,115 gene duplications and 119 million additional base pairs of genetic material compared to the present human genome used as a research reference.
It will help scientists and medical professionals better understand how genetic variations affect health, disease, and transit to the future in which genomic medicine benefits life.
The scientists found that their capacity to detect structural genetic variants increased by 104% when they used the pangenome instead of the present reference genome.
However, until now, the Pangenome Project is in the beginning stages.